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Alfonso Lagi MD. PhD, Internal Medicine Unit Villa Donatello Hospital - Firenze
Simone Cencetti MD, Ospedale Santa Maria Nuova Syncope Unit – Firenze
Introduction: the association between chronic constitutional hypotension (CCH) and symptoms is uncertain both as pathophysiological correlation as a statistical link. The study was undertaken in order to investigate the existence of a significant association between CCH and symptoms and identify the most represented ones.Methods: females only have been used because of the higher incidence of CCH in their sex. The symptoms considered were studied in three groups of subjects: A and B groups, identified for systolic arterial pressure (SAP) <100 mmHg and diastolic blood pressure (DAP) <60 mmH, and finally a C group of control consisting of normotensive women. Symptoms considered were: dizziness, anxiety / or depression, asthenia and / or fatigue, transient loss of consciousness (TLC), accidental falls, and body mass index (BMI).Results: patients with CCH had significant incidence of anxiety / depression and asthenia / fatigue and TLC versus controls. Individuals with PAD <60 mmHg (group B) had a significance statistical difference of events also vs. the group A.Discussion and conclusion: the females with CCH are symptomatic and have a lower BMI than controls. The low value of PAD defines a major risk group for TLC and a worse prognosis.
Gender based Retrospective observational study in symptomatic women
Cite this paper
Alfonso Lagi MD. PhD, Simone Cencetti MD, Syncope in Chronic Constitutional Hypotension: Gender based Retrospective observational study in symptomatic women, SCIREA Journal of Clinical Medicine. Vol. 1 , No. 1 , 2016 , pp. 38 - 48 .
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