Volume 3, Number 2 (2018)
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Home > Journals > SCIREA Journal of Chemistry > Archive > Paper Information

Synthesis of hydrofluoroethers (HFEs) as alternatives to CFCs

Volume 3, Issue 2, April 2018    |    PP. 13-24    |PDF (430 K)|    Pub. Date: September 25, 2018
1098 Downloads     915 Views  

Author(s)
Wei Li, Beijing Institute of Technology, 5 South Zhongguangcun Street, Haidian District, Beijing, 100081, P.R. China; Zhejiang Chemical Industry Research Institute Co., Ltd., Hangzhou 310023, P.R. China.
Zhikai Guo, Zhejiang Chemical Industry Research Institute Co., Ltd., Hangzhou 310023, P.R. China.
Hengdao Quan, Beijing Institute of Technology, 5 South Zhongguangcun Street, Haidian District, Beijing, 100081, P.R. China.

Abstract
A facile synthetic route for the preparation of a series of hydrofluoroethers (HFEs) was developed. This route was based on two key reactions. The first reaction involved the alcoholysis of various fluoroalcohols with p-toluenesulfonyl chloride in a sodium hydroxide solution, while the second involved the Williamson ether syntheses of the desired HFEs from the corresponding tosylates using sodium methoxide in methanol. As a result, a range of HFEs were synthesized using this mild and efficient method.

Keywords
hydrofluoroethers • alcoholysis • Williamson ether synthesis

Cite this paper
Wei Li, Zhikai Guo, Hengdao Quan, Synthesis of hydrofluoroethers (HFEs) as alternatives to CFCs, SCIREA Journal of Chemistry. Vol. 3 , No. 2 , 2018 , pp. 13 - 24 .

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