The Challenges and Solutions of Chiral Drug Preparation Techniques

Volume 9, Issue 1, February 2024     |     PP. 12-22      |     PDF (167 K)    |     Pub. Date: January 16, 2024
DOI: 10.54647/chemistry350041    7 Downloads     597 Views  


Zhao Mingrui, College of Pharmacy, Henan Medical College, Zhengzhou,451191, China
Shi Xiufang, School of Pharmaceutical Sciences, Zhengzhou University, Henan, Zhengzhou 450000, China
Yang Ninghui, College of Pharmacy, Henan Medical College, Zhengzhou,451191, China

To explore the challenges faced by chiral drug preparation techniques and propose corresponding solutions, We introduce the background and significance of chiral drug preparation technology, Subsequently, we analyze in detail various challenges faced in the current preparation of chiral drugs, including selectivity in asymmetric synthesis, substrate conversion rate, and catalyst selection. In order to address these challenges, a series of solutions, including the use of novel catalysts, optimization of reaction conditions, and improvements in reaction processes were proposed. Through the application of these solutions, various difficulties in the process of chiral drug preparation were successfully overcome, achieving efficient and selective synthesis. The discoveries of these research findings have important theoretical and practical implications for the preparation of chiral drugs and pharmaceutical development. In future research, we will continue to improve chiral drug preparation techniques to enhance synthesis efficiency and yield, at the same time, to meet the demands for drug therapy. In conclusion, this paper provides a detailed exploration of the challenges and solutions in chiral drug preparation technology, offering valuable references for research in this field.

Chiral Drug Preparation Techniques, Challenges, Solutions, Chiral Drug

Cite this paper
Zhao Mingrui, Shi Xiufang, Yang Ninghui, The Challenges and Solutions of Chiral Drug Preparation Techniques , SCIREA Journal of Chemistry. Volume 9, Issue 1, February 2024 | PP. 12-22. 10.54647/chemistry350041


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