Volume 4, Number 1 (2019)
Year Launched: 2016
Journal Menu
Previous Issues
Why Us
-  Open Access
-  Peer-reviewed
-  Rapid publication
-  Lifetime hosting
-  Free indexing service
-  Free promotion service
-  More citations
-  Search engine friendly
Contact Us
Email:   service@scirea.org
Home > Journals > SCIREA Journal of Clinical Medicine (ISSN: 2706-8870) > Archive > Paper Information

Analysis of Detection Results of Hepatitis B Virus Serological Markers in College Students

Volume 4, Issue 1, February 2019    |    PP. 1-10    |PDF (222 K)|    Pub. Date: March 23, 2019
72 Downloads     577 Views  

Li-fa Xu, School of Medicine, Anhui University of Science & Technology, Huainan 232001, Anhui, China
Chang-hao Hou, School of Medicine, Anhui University of Science & Technology, Huainan 232001, Anhui, China
Xiao-huan Lu, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei, China

Background: According to WHO estimates, more than 2 billion people worldwide have been infected with Hepatitis B Virus, and hepatitis B has seriously harmed human health.Objective: This study aims to understand the current status of hepatitis B infection in college students, to explore the performance patterns and composition ratios of hepatitis B virus serum markers, and to propose corresponding preventive measures for the diagnosis and treatment of hepatitis B infection in colleges and universities. Methods: In this paper, 681 people were selected from the four grades of a university by random sampling method. A total of 2724 college students were used to detect two pairs of serum hepatitis B by ELISA. At the same time, the corresponding questionnaires were conducted. Results: A total of 1947 hepatitis B virus serum markers were detected in 2724 serum samples, and the total positive rate was 71.5%. The hepatitis B virus serum markers formed a total of 7 serological patterns. The positive rates of HBsAg, HBeAg and anti-HBcAg were 1.32%, the positive rates of HBsAg, anti-HBc and anti-HBe were 0.44%, and the positive rates of anti-HBs and HBsAg were 0.44% and 0.55%, respectively, and the positive rate of total infection group was 2.75%. At the same time, the factors that affect the total positive rate of hepatitis B include: whether the vaccine is vaccinated, whether the birth place is rural or urban; the factors affecting the single positive rate of serum anti-HBs markers also include gender. Conclusion: The HBsAg positive rate of hepatitis B virus serological markers in college students is lower than the national average. The hepatitis B vaccine for college students is the most effective preventive method for active immunization of hepatitis B. Colleges and universities should strengthen health education interventions, isolate patients early, and strive for full coverage of hepatitis B vaccine.

College Students, Serological Markers, Serological Testing, HBV

Cite this paper
Li-fa Xu, Chang-hao Hou, Xiao-huan Lu, Analysis of Detection Results of Hepatitis B Virus Serological Markers in College Students, SCIREA Journal of Clinical Medicine (ISSN: 2706-8870). Vol. 4 , No. 1 , 2019 , pp. 1 - 10 .


[ 1 ] WHO.Global hepatitis report,2017[EB/OL].[2018-04-01].http://www.who.int/hepa-titis/publications/global-hepatitis-report2017/en/.
[ 2 ] WHO.Hepatitis B fact sheets[EB/OL].[2018-05-25]. http://www.who.int/news-roo-m/fact-sheets/detail/hepatitis-b.
[ 3 ] The Polaris Observatory Collaborators, Global prevalence, treatment,and preven-tion of hepatitis B virus infection in 2016:a modellingv study[J].Lancet Gastroenterol Hepatol,2018,3(6):383-403.
[ 4 ] Zhao R, Liu Q, Zhuang GH.A meta-analysis of the test results of five indicators for hepatitis B virus of college freshmen in current mainland China[J].Zhonghua Yu Fang Yi Xue Za Zhi,2018, 52(8):849-854.
[ 5 ] Ng KP,Ngeow YF,Kr MR.Hepatitis B seroprevalence among university of Malaya students in the post universal infant vaccination era. Med J Malaysia,2013,68(2):144- 147.
[ 6 ] Liu S,Gong LY.Six-year follow-up observation on the immune effect of hepatitis B vaccine[J].Chinese school health,1997,18(6):450-51.
[ 7 ] Lu Y, Liang XF, Wang FZ,et al.Hepatitis B vaccine alone may be enough for preventing hepatitis B virus transmission in neonates of HBsAg (+)/HBeAg (-)mothers[J].Vaccine,2017,35: 40-45.
[ 8 ] Liu YR,Han PF.Detection and Analysis of Serum Markers of Hepatitis B Virus in 4741 Cases of Physical Examination[J].Hubei Journal of Preventive Medicine, 2001,12(2):29-30.
[ 9 ] Zhang YL, Zhang XV, He F.A "two-and-a-half" and ALT test for hepatitis B in a school from 2004 to 2007[J]. Medical Animal Control, 2008, 24(9): 709.

Submit A Manuscript
Review Manuscripts
Join As An Editorial Member
Most Views
by Syed Adil Hussain, Taha Hasan Associate Professor
2283 Downloads 17135 Views
by Omprakash Sikhwal, Yashwant Vyas
2355 Downloads 14590 Views
by Munmun Nath, Bijan Nath, Santanu Roy
2249 Downloads 14440 Views
Upcoming Conferences